Two very, very indy dev games.
Bright Sun Studios ended up abandoning the project but
Highschool Crush Simulator*. It's a Ren'Py visual novel. There is a
mod that restores the zoo content that a crowd funding site forced the creator to cut so they could receive the money. You play as a female protagonist in the mostly lesbian focused story. You can play a monogamy or polyamory focused story. That said, there are a few male options. There is a futa character as well. The beast scenes are a bit limited. Really only the main character can reliably access zoo content but there is a second character that you learn shares the kink. Sadly, the most recent update left the game unfinished and abandoned. I still think it's worth it if you like the visual novel style.
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*Despite the name it takes place at a college and all characters are explicitly 18-21+
RPGM game
The Hunter is another option. Fair warning on this one, there is a ton of content in this that is intended to shock and gross out the player. It's another fem protag game. In this one you live in a women-only village set in post-apocalyptic world. Kaya, the main character, is training to become a Hunter. She basically finds and trains creatures at the request of other women to use as sex objects. There are dogs, horses, zombies, giant insects, mutants, and plenty more creatures to find, sexually train, and then sell to the women who request them. As stated, the game has extreme content. That includes scat, zombies that ejaculate maggots when they cum, piss, hardcore bdsm, varied consent, group sex, and gore. Most characters are bisexual and capable of hooking up the protagonist/other women as well as the beasts. This one also features a futa character. The game features a "combat" system which is where most of the sex and sex animation happens. The overworld is sprite/pixel style. There are character interactions with high-res visual style models too--which all also feature sex. The project was completed though I only played up to v.017 and the creator apparently made a
sequel as well. I can't speak to the quality of the story or sequel since I never finished the first. It wasn't bad but the amount of shock content is pretty high.
Screenshots available on the f95zone pages.